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Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 421-430 doi: 10.1007/s11684-015-0424-9

Abstract: Podoplanin (PDPN) is a mucin-type O-glycoprotein expressed in diverse cell types, such as lymphaticendothelial cells (LECs) in the vascular system and fibroblastic reticular cells (FRCs) in lymph nodesThis mechanism is required to initiate and maintain separation of blood and lymphatic vessels and toThis review provides a comprehensive overview of the roles of PDPN in vascular development and lymphoidorgan maintenance and discusses the mechanisms that regulate PDPN expression related to its function

Keywords： podoplanin     CLEC-2     Prox1     O-glycosylation     lymphatic vascular development and maintenance     lymphoid    

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Development and application of an off-site maintenance system in the petrochemical industry

Ruisheng YONG, Yanbing YE, Hanbin LUO, Lieyun DING

Frontiers of Engineering Management 2017, Volume 4, Issue 2,   Pages 111-126 doi: 10.15302/J-FEM-2017027

Abstract: On-site maintenance (ONSM) is critical to ensuring the safety of equipment in the petrochemical industryexposure to hazards during on-site operations and thereby reduce the probability of accidents, off-site maintenance

Keywords： on-site maintenance     petrochemical industry     safety     off-site maintenance system    

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Application and Development of Civil Aviation Condition Based Maintenance Decision Optimal Model

Zhang Haijun,Zuo Hongfu,Liang Jian,Rong Xiang

Strategic Study of CAE 2005, Volume 7, Issue 11,   Pages 17-20

Abstract:

At present the main maintenance's manner in the civil aviation field is condition based maintenancewhich may improve enormously maintenance's efficiency and econmy.Maintenance optimal model concentrates the essence of condition based maintenance and plays an importantrole in reducing maintenance cost and raising profit of civil aviation corporation.Markov decision Model, and analyzed these models’ shortcoming in application and prospected their development

Keywords： condition based maintenance     maintenance optimal model     decision     cost    

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Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 164-170 doi: 10.1007/s11684-009-0038-1

Abstract: The expressions of E-cadherin (E-Cad), N-cadherin (N-Cad), vascular endothelial cell growth factor (VEGFHigher microvascular density (MVD) was also found to be significantly associated with lymphatic metastasis

Keywords： epithelial-mesenchymal transition     vascular endothelial cell growth factor     matrix metalloproteinase-9    

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Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Wei Zhuo, Yang Chen, Xiaomin Song, Yongzhang Luo

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 336-340 doi: 10.1007/s11684-011-0163-5

Abstract: Recently, several studies demonstrated that endostatin also inhibits tumor lymphangiogenesis and lymphatic

Keywords： endostatin     angiogenesis     lymphangiogenesis     nystatin     internalization     tumor    

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Risk evaluation for the task transfer of an aircraft maintenance program based on a multielement connection

Frontiers of Engineering Management doi: 10.1007/s42524-023-0282-0

Abstract: This paper proposes a framework for evaluating the efficacy and suitability of maintenance programs witha focus on quantitative risk assessment in the domain of aircraft maintenance task transfer.The analysis is anchored in the principles of Maintenance Steering Group-3 (MSG-3) logic decision paradigmsThe paper advances a holistic risk assessment index architecture tailored for the task transfer of maintenanceThis analytical construct serves to streamline the process of risk assessment pertinent to maintenance

Keywords： risk evaluation     maintenance steering group     analytic network process     task transfer     maintenance program    

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Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 177-180 doi: 10.1007/s11684-009-0021-x

Abstract: To evaluate the mechanism of vascular endothelial growth factor (VEGF) on the prevention of restenosisangioplasty, the recombinant adenovirus vector containing hVEGF cDNA was constructed and transfected into vascular

Keywords： vascular endothelial growth factors     restenosis     reactive oxygen species     endothelial cells     vascular smooth    

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Human reliability in maintenance task

Pacaiova HANA,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 2,   Pages 184-188 doi: 10.1007/s11465-010-0002-4

Abstract: Maintenance management requirements have another dimension in the present as in the past.This paper presents the concept of a maintenance management task and its function in preventing majorThe importance of considering the reliability of maintenance tasks and the method to reach it are also

Keywords： maintenance     risk assessment     failure     reliability     prevention    

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Crk-associated substrate, vascular smooth muscle and hypertension

TANG Dale

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 323-331 doi: 10.1007/s11684-008-0062-6

Abstract: Hypertension is characterized by vascular smooth muscle constriction and vascular remodeling involvingEvidence for the role of CAS in the regulation of vascular smooth muscle contractility is presented.which activates neuronal Wiskott-Aldrich syndrome protein (N-WASP)-mediated actin assembly and force developmentThese new findings establish the important role of CAS in the modulation of vascular smooth muscle functionsFurthermore, the upstream regulators of CAS may be new biologic targets for the development of more effective

Keywords： Contraction stimulation     phosphatase-proline     molecular structure     discovered     hypertension    

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Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 284-286 doi: 10.1007/s11684-009-0062-1

Abstract: To evaluate the role of nitric oxide in the biological effects of vascular endothelial growth factor(VEGF) and the possible mechanism of VEGF, the cultured vascular endothelial cells of rabbit aorta wereThe absorbance () value of vascular endothelial cells and the levels of prostaglandin (PGI), endothelinVEGF could promote the proliferation and secretion of PGI and inhibit the secretion of ET-1 and vWF in vascularoxide is an important mediator in the process of stimulating proliferation and regulating secretion of vascular

Keywords： vascular endothelial growth factor     nitric oxide     N-nitro-L-arginine methyl ester     vascular endothelial    

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Progress in tumor vascular normalization for anticancer therapy: challenges and perspectives

Bingxue Shang, Zhifei Cao, Quansheng Zhou

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 67-78 doi: 10.1007/s11684-012-0176-8

Abstract: In 2001, Jain proposed tumor vascular normalization as an alternative approach to treating cancers basedPreclinical and clinical data have shown that tumor vascular normalization using monoclonal antibodiesHowever, current tumor vascular normalizing drugs display moderate anticancer efficacy.Therefore, multiple-targeting of vasculogenic tumor cells and genes may improve the efficacy of tumor vascularTo this end, the combination of antiangiogenic drugs with tumor vascular normalizing therapeutics, as

Keywords： angiogenesis     vasculogenesis     neovascularization     tumor     vasculature     normalization     traditional Chinese medicine    

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sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascular

Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 320-329 doi: 10.1007/s11684-016-0463-x

Abstract: Rat aortic vascular smooth muscle cells (VSMCs) were treated with phosphate buffer solution or 500 µ

Keywords： p-cresyl sulfate     atherosclerosis     plaque stability     vascular smooth muscle cell    

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Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 403-409 doi: 10.1007/s11684-017-0522-y

Abstract: However, the role of endogenous TFPI in vascular smooth muscle cells (VSMCs) in thrombosis and vasculardisease development has yet to be elucidated.establish TFPI conditional knockout mice and to examine the effects of VSMC-directed TFPI deletion on development

Keywords： arterial thrombosis     conditional knockout mice     tissue factor pathway inhibitor     vascular smooth muscle    

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A review of condition-based maintenance: Its prognostic and operational aspects

Yanrong LI, Shizhe PENG, Yanting LI, Wei JIANG

Frontiers of Engineering Management 2020, Volume 7, Issue 3,   Pages 323-334 doi: 10.1007/s42524-020-0121-5

Abstract: Condition-based maintenance (CBM) detects early signs of failure and dictates when maintenance should

Keywords： condition-based maintenance     prognostics     operational decision-making     reliability    

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Trend prediction technology of condition maintenance for large water injection units

Xiaoli XU, Sanpeng DENG

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 2,   Pages 171-175 doi: 10.1007/s11465-009-0091-0

Abstract: Trend prediction technology is the key technology to achieve condition-based maintenance of mechanicalThe traditional preventive maintenance is not economical and cannot completely avoid vicious accidentsTo ensure the normal operation of units and save maintenance costs, trend prediction technology is studiedto achieve condition-based maintenance for water injection units.change of the water injection units and provide technical means to achieve condition-based predictive maintenance

Keywords： water injection units     condition-based maintenance     trend prediction    

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Title Author Date Type Operation

Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Journal Article

Development and application of an off-site maintenance system in the petrochemical industry

Ruisheng YONG, Yanbing YE, Hanbin LUO, Lieyun DING

Journal Article

Application and Development of Civil Aviation Condition Based Maintenance Decision Optimal Model

Zhang Haijun,Zuo Hongfu,Liang Jian,Rong Xiang

Journal Article

Lymphatic metastasis is related to the epithelial-mesenchymal transition and expressions of VEGF, MMP

Lihui WANG, Lianhong LI, Shen LV, Shujun FAN, Li ZHAN, Bo WANG, Zhong ZHANG

Journal Article

Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Wei Zhuo, Yang Chen, Xiaomin Song, Yongzhang Luo

Journal Article

Risk evaluation for the task transfer of an aircraft maintenance program based on a multielement connection

Journal Article

Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Journal Article

Human reliability in maintenance task

Pacaiova HANA,

Journal Article

Crk-associated substrate, vascular smooth muscle and hypertension

TANG Dale

Journal Article

Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Journal Article

Progress in tumor vascular normalization for anticancer therapy: challenges and perspectives

Bingxue Shang, Zhifei Cao, Quansheng Zhou

Journal Article

sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascular

Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin

Journal Article

Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Journal Article

A review of condition-based maintenance: Its prognostic and operational aspects

Yanrong LI, Shizhe PENG, Yanting LI, Wei JIANG

Journal Article

Trend prediction technology of condition maintenance for large water injection units

Xiaoli XU, Sanpeng DENG

Journal Article